Iodophenpropit

Iodophenpropit

Iodophenpropit

Chemical compound


Iodophenpropit is a histamine antagonist which binds selectively to the H3 subtype. Its 125I radiolabelled form has been used for mapping the distribution of H3 receptors in animal studies.[1][2]

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References

  1. Jansen, FP; Wu, TS; Voss, HP; Steinbusch, HW; Vollinga, RC; Rademaker, B; Bast, A; Timmerman, H (1994). "Characterization of the binding of the first selective radiolabelled histamine H3-receptor antagonist, 125I-iodophenpropit, to rat brain". British Journal of Pharmacology. 113 (2): 355–62. doi:10.1111/j.1476-5381.1994.tb16995.x. PMC 1510107. PMID 7834183.
  2. Jansen, FP; Mochizuki, T; Maeyama, K; Leurs, R; Timmerman, H (2000). "Characterization of histamine H3 receptors in mouse brain using the H3 antagonist 125Iiodophenpropit". Naunyn-Schmiedeberg's Archives of Pharmacology. 362 (1): 60–7. doi:10.1007/s002100000227. PMID 10935534. S2CID 21293180.

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