Inositol hexakisphosphate kinase 1 is an enzyme that in humans is encoded by the IP6K1 gene.^[5]

Quick Facts IP6K1, Identifiers ...

IP6K1
Identifiers
Aliases	IP6K1, IHPK1, PiUS, inositol hexakisphosphate kinase 1
External IDs	OMIM: 606991; MGI: 1351633; HomoloGene: 56602; GeneCards: IP6K1; OMA:IP6K1 - orthologs
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3p21.31 Start 49,724,294 bp[1] End 49,786,542 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 F1 Start 107,879,700 bp[2] End 107,925,981 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in middle frontal gyrus frontal pole prefrontal cortex Brodmann area 10 stromal cell of endometrium cingulate gyrus Brodmann area 9 cerebellar vermis nucleus accumbens ganglionic eminence Top expressed in spermatid spermatocyte dorsomedial hypothalamic nucleus cerebellar cortex superior frontal gyrus habenula subiculum paraventricular nucleus of hypothalamus entorhinal cortex supraoptic nucleus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function inositol hexakisphosphate 5-kinase activity transferase activity inositol hexakisphosphate 1-kinase activity nucleotide binding ATP binding inositol hexakisphosphate 3-kinase activity kinase activity inositol-1,3,4,5,6-pentakisphosphate kinase activity inositol 5-diphosphate pentakisphosphate 5-kinase activity inositol diphosphate tetrakisphosphate kinase activity inositol heptakisphosphate kinase activity protein binding inositol hexakisphosphate kinase activity Cellular component cytoplasm nucleus nucleoplasm fibrillar center cytosol Biological process phosphatidylinositol phosphate biosynthetic process inositol phosphate metabolic process phosphorylation inositol phosphate biosynthetic process negative regulation of cold-induced thermogenesis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9807 27399 Ensembl ENSG00000176095 ENSMUSG00000032594 UniProt Q92551 Q6PD10 RefSeq (mRNA) NM_153273 NM_001006115 NM_001242829 NM_013785 NM_026266 RefSeq (protein) NP_001006115 NP_001229758 NP_695005 NP_038813 Location (UCSC) Chr 3: 49.72 – 49.79 Mb Chr 9: 107.88 – 107.93 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Close

This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Alternative splicing occurs for this gene; however, the full-length nature of all transcript variants has not yet been described.^[5]