Ric Griffin arrives to replace Mr. Barratt. Mr. Meyer is involved in a road accident with serious injuries. The wife of the other accident victim is seen by Alex driving around in Meyer's car. He investigates.

First Appearance of Ric Griffin

After Ric Griffin removes the bullet from Mr Meyer's spine, Meyer proves to be a troublesome patient. During Sandy's 20th birthday party, Keri and Liam get into a regretful situation. Danny tries to help an illegal immigrant.

Keri thinks she was raped by Liam and Janice catches her taking the morning after pill. Liam returns Keri's necklace and acts like nothing is wrong. A 14 year old boy Ben makes sexual innuendo's towards Keri, and slaps her. The illegal immigrant Maria, leaves the hospital with her child.

A woman who has waited for a year to have surgery jumps the queue by going to the newspapers. Janice announces at a dinner party that she is pregnant. Liam questions Keri why she is being so cold towards him after they slept together. She tells him that he raped her. Steve pulls him aside and Janice takes Keri to her office for questioning.

Tribunal day. Danny has an emergency and does not show up as a witness against Liam. Liam thinks Danny is siding with him. Maria has run away from the hospital again, but this time she leaves her son and Danny goes to look for her. Sandy is no help in her testimony. During a break, Liam follows Keri into the washroom and pleads with her not to go through with it, still not admitting any guilt.

A bus driver is devastated that he hit a pedestrian. Meanwhile the pedestrian is also in the hospital across from his room and tells the staff that it was a suicide attempt. The drivers friend overhears this and confronts him.

After Janice loses the baby, Alistair asks her to wait before trying again. Chrissy offers him her shoulder to cry on. Danny approaches Social Services to see if Maria can stay in the country. Liam and Sandy are annoyed at Danny for letting Maria move in with them.

It is Danny and Maria's wedding day. Kath has one last go to try to stop the sham wedding. A young girl has a inoperable tumor and Keri tells her she is dying before her parents do.

A convict with a brain tumor offers her liver to a dying girl. She murdered her own daughter, and wants to make amends before she dies. Danny is starting to regret his marriage to Maria.

Steve leaves Robbie to look after his wife Emma and she has an accident with tragic results. Alex and Sam sort out their differences. A blind man gets his sight back after surgery on his stomach. Meyer investigates this "miracle".

Maria finally kisses Danny. A heart patient has two wives who do not know about each other until today. Steve's son Robbie is rushed to hospital with alcohol poisoning. Steve and Robbie come to terms with Emma's death. Alistair professes love for Chrissy and she breaks it off. We see Chrissy's name badge under the bed where Janice is lying.

A rugby player gets a broken leg in a match. He dies from a brain bleed. After investigating, it is revealed that his best friend punched him in the head and caused it. Janice finds Chrissy's name badge and confronts Alistaire and he weasels his way out of it. He gives her the necklace that he bought for Chrissy. Janice is pregnant.

New year's eve party. Alex leaves early, but promises to get back to Sam. While he is gone, he saves a man in a road traffic accident, and runs over a little boy. The police give him a breathalyzer and he fails. Sam is annoyed that he did not come back. A former girlfriend brings her little girl to the hospital and Alex thinks it may be his daughter.Alistaire starts annoying Chrissy, and she rejects him again.

Alex can't figure out why he was positive when he only had 1 drink 2 hours before the test. Sam seems to know something about it. The little boy Alex ran down dies, and his parents find out he was considered drunk. They threaten to sue. Alistaire is ready to leave Janice, and in the parking lot, he physically tries to throw Chrissy into her car. A fight breaks out with Owen over Chrissy and Janice witnesses it, then sees his packed bag in their car. She leaves without him.

The affair becomes public because of Alastair and Owen's fight. A little boy needs a bone marrow transplant, but both his parents don't match. His mother calls her ex boyfriend who happens to be her husband's best friend. Luka's birthday party and Kath is worried about Simon's drinking. Maria's ex show up and Danny gets the sofa. In a drunken rage, Simon hits Kath. A couple bring their son in for a bone marrow transplant and find out the husband's DNA does not match his son. His wife confesses she slept with his best friend 12 years ago. Birthday party for Maria's son. Kath and her husband Simon quarrel over his drinking.

Danny sees Kath's black eye and beats up his father Simon. Marija has to choose between Danny and her ex husband Goran. Sam admits to Chrissy that she spiked Alex's drink at the New Year's party.

Sandy meets a new guy Ben at a club, only to find out that he is starting work at Holby City tomorrow, as a midwife. A cancer patient finds out that he is going to die before the birth of his baby. His wife decides to induce her labour so he can see his child before he dies. Danny makes up with Kath for hitting Simon.

Chrissy tells Sam that she will tell Alex that Sam spiked his drinks. Sam goes to Alex, and as she is about to tell him, he tells her he loves her. A man who was a bully at school, gets a bed next to a man who was his victim, with unfortunate results.

Court for Alex today. Fran lies about her son's accident. Alex breaks down on the stand, and during the recess, Sam tells him what she did. Then she begs Fran to tell the truth, and tells her she spiked the drinks.

Stan's wife collapses in the car park and is admitted. Sam swears off men. Chloe, a young girl with learning disabilities is about to have a hysterectomy and it is her mother's decision.

Alex tries to get Sam fired by telling Meyer about the spiked drink. Meyer won't do it because she was off duty. Ben decides to invite his parents for dinner to tell them he's gay. He asks Sandy to come for moral support. Problem is, Sandy recognizes them from the cancer ward.

Kath is embarrassed by her black eye. She meets a patient who she thinks is being abused by her husband, and tries to convince her to go to the police. The woman won't admit he hits her. Ric Griffin finds out that the college money he gave his daughter Jess, has been used for breast enhancement and she wants more money for a modeling career. He cuts her off and tells her to get a real job and earn it.

Kath is helping Father Chambers with Communion and is late home. Simon gets really angry about it. Tash gets pricked by a heroin needle in her new girlfriend's purse. She breaks off with her and the girl begs her to help her quit. Kath is lying on the floor with a bloody face and calls an ambulance and passes out. Danny is called when Kath is admitted and swears he will kill his father. He is about to do just that when there is someone at the door.

Kath leaves Simon and gets Danny to pick up her belongings. Father Chambers and Danny paint and decorate her new place while she is at work. A woman wants to leave the man that cared for her and raised her two sons, for another man, who happens to be her husband's much younger employee.

A woman wants to abandon her little boy because the doctors gave him a transfusion. She considers her son impure now and doesn't want him. Tash gets her HIV test results from the needle prick.

Samantha invites Alex to her birthday party, but he declines. He meet Jess in a bar, and she takes him to the party. He finds out Jess is Ric's daughter and she is flatmates with Samantha. A fight breaks out with Steve and his old friend. Police come, Ric calls them racist, he gets arrested for not cooperating.

Meyer tells Ric off for getting arrested for marijuana. Steve finds a lump on a little boy's neck. Janice has a positive scan. Ric goes for an administrative job at a private clinic, then changes his mind. Alistair wants to settle the divorce.

Liam goes next door because of a loud stereo disturbing his sleep and gets drawn in to a family abuse situation. The father has beaten the mother, and is trying to suffocate his son. Liam and the man get in a scuffle and they both go over the balcony.

Liam wakes up from his coma. Simon disputes Kath's divorce papers. A woman who cannot have children kidnaps a baby from its sleeping mother. Keri forgives Liam for raping her.

Samantha catches Alex leaving the flat after he slept with Jess. Liam is paralyzed. Owen's daughter is discharged. Alex tells Jess that he does not want a relationship and breaks her heart.

Meyer and Alex take sides about whether to give a Down Syndrome man a heart transplant. Kath feels her relationship with Father Chambers is moving too fast. Ric's son Leo joins the team.

Liam is discharged and can't cope with people feeling sorry for him. Jess is pregnant with Alex's baby and Samantha tries to influence her to abort the baby.

Kath wants to break off with Michael, but he has sent a letter of resignation. Liam is acting fine and happy, but when no one is home he is suicidal. Michael tries to kill himself. Kath tells him that she never wants to see him again.

While Ric is planning his birthday, his daughter Jess is still undecided about an abortion that has been scheduled for today.

After taking Owen back after his affair with Chrissy, Laura struggles to make her family whole again. Liam is considering if he could go back to Holby and do his job properly in a wheelchair.

There is a charity auction with the men of Holby. A few of them are nervous about who will bid on them. Pam McGrath starts today as the new Risk manager, and has turned a few heads on day one.

Tash's old girlfriend Mel comes back, only to give her disturbing news. Mubbs makes a grave error and a baby may not survive because of it.

Keri gets her date with Mubbs that she won in the auction. Keri's mother Pam interrupts it and Mubbs feels awkward because earlier that day he was intimate with Pam.

Owen is getting involved with Chrissy again. The new registrar Diane Lloyd in one of Ric's old girlfriends. Sam gives Ric a cheque to clear his debts, and on his stag night, he goes to the casino to wager the whole thing.

Samantha and Ric's wedding day arrives. Alex wants to go to Sam and tell her of his true feelings, and what Ric did with her money. Sam is having big doubts about the wedding because she still has feelings for Alex.

Alistair is back at Holby to ask a very pregnant Janice for a divorce. Keri walks in on Mubbs and her mother Pam while they are supposed to be having a meeting and is shocked by what she sees.

Now that Owens daughter Katie knows about Chrissy, he is on edge. Danny invites Lisa to live with him and Sandy. Sandy is angered that he did not consult her.

Janice's pregnancy goes awry and undergoes an emergency c-section; both mother and baby are left fighting for their lives as a result. Sam goes behind Mr Meyer's back to convince the familty of an ill boy not to go ahead with his planned operation, with disastrous results. Owen is forced to leave Katie with Chrissy while he operates on Janice; a disgruntled Chrissy fails to supervise Katie, and the latter suffers burns when she acciedently pours scalding milk on her arm.

Note: Joanna Roth guest stars

Meyer's team operate on the young heart patient, but the delay proves fatal. Alex admits to Meyer that Sam talked the parents out of his having the operation initially; Meyer fires Sam and blackballs her from the medical profession. After trying to convince Alex to resign with her and being turned down, she then tries to rekindle her relationship with Ric - who sees through her motives for reconciliation and turns her down also. Alaistair defies Meyer's instructions and operates on his own daughter: however, Meyer proves forgiving, and even assists on the operation. As a result, the baby survives, and Owen does enough in theatre to save Janice. The episode ends with Sam confronting Jan Goddard (making a cross-over appearance from Casualty) about Meyer and making it clear she won't go quietly.

Note: the episode saw the conclusion of two long-running storylines in the series, those being Janice's pregnancy and the Alex Adams-Sam Kennedy on-off romance. It was also the last time Otter Ward was shown in the show; and the episode also saw the beginning of the events that led to the departure of Anton Meyer.

Sam has launched a complaint against Meyer and he is under investigation. Some of the other doctors believe the allegations by Sam to be true. Is Chrissie responsible for Owen's daughters burns?

First appearance of Tom Campbell-Gore & Ed Keating. Jan Goddard makes another cross-over appearance from Casualty.

Meyer breaks his operating ban to save a child. He is exonerated, but resigns. He is leaving for the USA and Alex is going with him. Chrissie has a house warming party without Owen's knowledge. Mubbs and Lisa get back together.

Final Appearance of Anton Meyer.

Note: Although not officially the end of Series 4, in many respects this episode marked a new chapter in the show's history, with the departure of George Irving's Anton Meyer removing the last link from the first series.

The new consultant is Tom Campbell-Gore, the very Doctor who investigated Meyer. Ric and him have words over a patient.

Chrissie and Owen's relationship becomes strained and Owen looks to his work as a distraction. Ric performs radical surgery on a teenage boy, with bad results.

Ed Keatings; ex wife shows up to a football match with her new boyfriend and they have words. Ed punches him and he has a heart attack. Lisa's dad Terry has a tumour and he keeps it from her.

Robbie Waring's friends steal drugs from the ward. Steve chases them and one of them get hurt. Terry Fox's surgery is successful.

Also featured for the first time in this episode is The Acute Admissions Unit, or simply AAU, is a short-stay department located on the ground floor of Holby City Hospital. Its purpose is to provide rapid treatment of acute cases that have either been directly admitted to the department or transferred from the emergency department.

Terry decides to get a divorce after his surgery. Diane keeps a distance from Danny after he had his friends to her apartment for a party without her knowledge.

Terry convinces Kath to divorce Simon. Simon shows up on the ward and attempts to beat her up. Katie's 10th birthday party is a disaster.