Lettuce also was a model and client of Stephen "Suede" Baum during a challenge in the fifth season of Project Runway. While on the show, she had several disagreements with Suede, especially over his not designing gloves for her, which caused her to call him "lazy". This led to designer Jerell Scott using the name "Hedda Lettuce" as a term for a model that is hard to work with.
Lettuce appeared on the April 27, 2009, show of The Tyra Banks Show. The guests on the show took part in a social experiment called Gay Kingdom. They voted on roles for each member of the kingdom ranging from king and queen to concubine and pauper; Lettuce was labeled as the jester of the kingdom.
Lettuce appeared on an episode of Ugly Betty entitled "Chica and the Man" in which Wilhelmina Slater discovered she had a drag impersonator named Wilhediva Hater. Although she had little dialogue, Hedda can be seen in the majority of the scenes that take place in the drag bar.
In 2010, Lettuce was featured in the web series Queens of Drag: NYC by gay.com in 2010. The series featured fellow New York drag queens Bianca Del Rio, Dallas DuBois, Lady Bunny, Mimi Imfurst, Peppermint, and Sherry Vine.
Lettuce provides commentary on the special features of the 2021 blu-ray edition of the 1981 film Mommie Dearest based on the book by Joan Crawford's daughter, Christina.