HLA-B78

HLA-B78

HLA-B78

Genetic HLA-B serotype

HLA-B78 (B78) is an HLA-B serotype. The serotype identifies the more common HLA-B*78 gene products.[1] B78 is more common in West and North Africa, but is also scattered at low frequencies in parts of Asia. (For terminology help see: HLA-serotype tutorial)

major histocompatibility complex (human), class I, B78
Alleles B*7801
B*7802
Structure (See HLA-B)
Symbol(s) HLA-B
EBI-HLA B*7801
EBI-HLA B*7802
Locus chr.6 6p21.31

Serotype

B78 serotype recognition of some HLA B*78 allele-group gene products[2]
B*78B78 otherSample
allele % %size (N)
78014148210

Allele frequencies

HLA B*7801 frequencies
freq
ref.Population(%)
[3]Fulani (Burkina Faso)8.2
[3]Bandiagara (Mali)6.9
[3]Niokholo Mandinka (Senegal)5.3
[3]Mossi (Burkina Faso)2.8
[3]Guinea Bissau2.3
[3]Akan Adiopodoume (Ivory Coast)2.3
[3]Tunis (Tunisia)2.3
[3]Berber (Morocco)1.4
[3]Rimaibe (Burkina Faso)1.1
[3]New Delhi (India)0.8
[3]Lisu (Yunnan, China)0.7
[3]Beti (Cameroon)0.6
[3]Majorca & Minorca (Spain)0.6
[3]Gypsy (E. Andalusia, Spain)0.5
[3]Tunisia0.5
[3]Romanian0.3
[3]Northeast Thailand0.2
[3]Tibet (China)0.6
'
HLA B*7802 frequencies
[3]Svans (Georgia)0.6
[3]Arab Druse (Israel)0.5
[3]Delhi (India)0.5
[3]Southern Han (China)0.2
[3]Beijing (China)0.1

References

  1. [1]
    Marsh, S. G.; Albert, E. D.; Bodmer, W. F.; Bontrop, R. E.; Dupont, B.; Erlich, H. A.; Fernández-Viña, M.; Geraghty, D. E.; Holdsworth, R.; Hurley, C. K.; Lau, M.; Lee, K. W.; Mach, B.; Maiers, M.; Mayr, W. R.; Müller, C. R.; Parham, P.; Petersdorf, E. W.; Sasazuki, T.; Strominger, J. L.; Svejgaard, A.; Terasaki, P. I.; Tiercy, J. M.; Trowsdale, J. (2010). "Nomenclature for factors of the HLA system, 2010". Tissue Antigens. 75 (4): 291–455. doi:10.1111/j.1399-0039.2010.01466.x. PMC 2848993. PMID 20356336.
  2. [2]
    derived from IMGT/HLA
  3. [3]
    Middleton, D.; Menchaca, L.; Rood, H.; Komerofsky, R. (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens. 61 (5): 403–407. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660.
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