Glutathione_amide_reductase

Glutathione amide reductase

Glutathione amide reductase

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Glutathione amide reductase (EC 1.8.1.16, GAR) is an enzyme with systematic name glutathione amide:NAD+ oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction

2 glutathione amide + NAD+ glutathione amide disulfide + NADH + H+
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Glutathione amide reductase is a dimeric flavoprotein (FAD).

References

  1. [1]
    Vergauwen B, Pauwels F, Jacquemotte F, Meyer TE, Cusanovich MA, Bartsch RG, Van Beeumen JJ (June 2001). "Characterization of glutathione amide reductase from Chromatium gracile. Identification of a novel thiol peroxidase (Prx/Grx) fueled by glutathione amide redox cycling". The Journal of Biological Chemistry. 276 (24): 20890–7. doi:10.1074/jbc.M102026200. PMID 11399772.
  2. [2]
    Vergauwen B, Van Petegem F, Remaut H, Pauwels F, Van Beeumen JJ (February 2002). "Crystallization and preliminary X-ray crystallographic analysis of glutathione amide reductase from Chromatium gracile". Acta Crystallographica Section D. 58 (Pt 2): 339–40. doi:10.1107/s0907444901020303. PMID 11807270.
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