Fluorenylmethyloxycarbonyl_chloride

Fluorenylmethyloxycarbonyl chloride

Fluorenylmethyloxycarbonyl chloride

Chemical compound


Fluorenylmethyloxycarbonyl chloride (Fmoc-Cl) is a chloroformate ester. It is used to introduce the fluorenylmethyloxycarbonyl protecting group as the Fmoc carbamate.

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Preparation

This compound may be prepared by reacting 9-fluorenylmethanol with phosgene:[2]


References

  1. Carpino, Louis A.; Han, Grace Y. (1972). "9-Fluorenylmethoxycarbonyl amino-protecting group". The Journal of Organic Chemistry. 37 (22): 3404. doi:10.1021/jo00795a005.

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