Family_with_sequence_similarity_19_member_A4,_C-C_motif_chemokine_like

Family with sequence similarity 19 member A4, C-C motif chemokine like

Family with sequence similarity 19 member A4, C-C motif chemokine like

Protein-coding gene in the species Homo sapiens

Family with sequence similarity 19 member A4, C-C motif chemokine like is a protein that in humans is encoded by the FAM19A4 gene. [5]

Quick Facts TAFA4, Identifiers ...

Function

This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Nov 2011].

References

  1. [1]
    GRCh38: Ensembl release 89: ENSG00000163377 – Ensembl, May 2017
  2. [2]
    GRCm38: Ensembl release 89: ENSMUSG00000046500 – Ensembl, May 2017
  3. [3]
    "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. [4]
    "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. [5]
    "Entrez Gene: Family with sequence similarity 19 member A4, C-C motif chemokine like". Retrieved 2017-12-09.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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