Estradiol_17β-benzoate

Estradiol 17β-benzoate

Estradiol 17β-benzoate

Chemical compound

Not to be confused with Estradiol benzoate.

Estradiol 17β-benzoate (E2-17B) is an estrogen and an estrogen ester—specifically, the C17β benzoate ester of estradiol—which was never marketed.[1][2][3] It is the C17β positional isomer of the better-known and clinically used estradiol ester estradiol benzoate (estradiol 3-benzoate; Progynon-B).[1] Estradiol 17β-benzoate was first described in the 1930s.[4]

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See also

References

  1. [1]
    Junkmann K, Witzel H (1957). "[Chemistry and pharmacology of steroid hormone esters]" [Chemistry and pharmacology of steroid hormone esters]. Zeitschrift für Vitamin-, Hormon- und Fermentforschung (in German). 9 (1–2): 97–143 contd. PMID 13531579.
  2. [2]
    Perez E, Cai ZY, Covey DF, Simpkins JW (2005). "Neuroprotective effects of estratriene analogs: structure-activity relationships and molecular optimization". Drug Development Research. 66 (2): 78–92. doi:10.1002/ddr.20047. ISSN 0272-4391. S2CID 86133327.
  3. [3]
    Yi KD, Perez E, Yang S, Liu R, Covey DF, Simpkins JW (March 2011). "The assessment of non-feminizing estrogens for use in neuroprotection". Brain Research. 1379: 61–70. doi:10.1016/j.brainres.2010.11.058. PMC 3048764. PMID 21111714.
  4. [4]
    Parkes AS (April 1937). "Relative duration of action of various esters of oestrone, oestradiol and oestriol". The Biochemical Journal. 31 (4): 579–585. doi:10.1042/bj0310579. PMC 1266977. PMID 16746375.


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