EAF2

EAF2
Identifiers
Aliases	EAF2, BM040, TRAITS, U19, ELL associated factor 2
External IDs	OMIM: 607659; MGI: 2146616; HomoloGene: 10208; GeneCards: EAF2; OMA:EAF2 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	121,886,526 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	36,695,365 bp
RNA expression pattern
	Top expressed in
	bone marrow cells; ; monocyte; ; lymph node; ; trabecular bone; ; appendix; ; kidney tubule; ; rectum; ; spleen; ; thymus; ; seminal vesicula;
	Top expressed in
	female urethra; ; proximal tubule; ; lacrimal gland; ; epithelium of urethra; ; seminal vesicula; ; male urethra; ; ejaculatory duct; ; kidney; ; salivary gland; ; submandibular gland;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding; protein binding;
Cellular component	nuclear speck; transcription elongation factor complex; super elongation complex; nucleus; nucleoplasm;
Biological process	positive regulation of transcription, DNA-templated; regulation of transcription, DNA-templated; negative regulation of cell growth; negative regulation of epithelial cell proliferation involved in prostate gland development; positive regulation of transcription by RNA polymerase II; transcription, DNA-templated; apoptotic process; transcription by RNA polymerase II; transcription elongation from RNA polymerase II promoter;
	Sources:Amigo / QuickGO
Orthologs
	55840
	106389
	ENSG00000145088
	ENSMUSG00000022838
	Q96CJ1
	Q91ZD6
	NM_018456; NM_001320041
	NM_001113401; NM_001113405; NM_134111; NM_001358102
	NP_001306970; NP_060926
	NP_001106872; NP_001106876; NP_598872; NP_001345031
	Wikidata
View/Edit Human	View/Edit Mouse

EAF2

Protein-coding gene in the species Homo sapiens

ELL-associated factor 2 is a protein that in humans is encoded by the EAF2 gene.^[5]^[6]^[7] It is part of the EAF family of proteins.

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This article uses material from the Wikipedia article EAF2, and is written by contributors. Text is available under a CC BY-SA 4.0 International License; additional terms may apply. Images, videos and audio are available under their respective licenses.

[refGRCh38Ensembl-1] [1]
GRCh38: Ensembl release 89: ENSG00000145088 – Ensembl, May 2017

[refGRCm38Ensembl-2] [2]
GRCm38: Ensembl release 89: ENSMUSG00000022838 – Ensembl, May 2017

[3] [3]
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] [4]
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12446457-5] [5]
Simone F, Luo RT, Polak PE, Kaberlein JJ, Thirman MJ (Feb 2003). "ELL-associated factor 2 (EAF2), a functional homolog of EAF1 with alternative ELL binding properties". Blood. 101 (6): 2355–62. doi:10.1182/blood-2002-06-1664. PMID 12446457.

[pmid12907652-6] [6]
Xiao W, Zhang Q, Jiang F, Pins M, Kozlowski JM, Wang Z (Aug 2003). "Suppression of prostate tumor growth by U19, a novel testosterone-regulated apoptosis inducer". Cancer Res. 63 (15): 4698–704. PMID 12907652.

[entrez-7] [7]
"Entrez Gene: EAF2 ELL associated factor 2".

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[7]

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[3]

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EAF2

EAF2

References

Further reading

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