Diosmetin
Diosmetin
Chemical compound
Diosmetin, also known as 5,7,3′-trihydroxy-4′-methoxyflavone, is an O-methylated flavone, a chemical compound that can be found in the Caucasian vetch.[1]
Quick Facts Names, Identifiers ...
| Names | |
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| IUPAC name
3′,5,7-Trihydroxy-4′-methoxyflavone | |
| Systematic IUPAC name
5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-benzopyran-4-one | |
| Other names
Luteolin 4′-methyl ether | |
| Identifiers | |
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| ECHA InfoCard | 100.007.539  |
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| Properties | |
| C16H12O6 | |
| Molar mass | 300.26 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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It has been found to act as a weak TrkB receptor agonist.[2]
- Andreeva, O. A.; Ivashev, M. N.; Ozimina, I. I.; Maslikova, G. V. (1998). "Diosmetin glycosides from caucasian vetch: Isolation and study of biological activity". Pharmaceutical Chemistry Journal. 32 (11): 595–597. doi:10.1007/BF02465832. S2CID 21434373.
- Jang SW, Liu X, Yepes M, Shepherd KR, Miller GW, Liu Y, Wilson WD, Xiao G, Blanchi B, Sun YE, Ye K (2010). "A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone". Proc. Natl. Acad. Sci. U.S.A. 107 (6): 2687–92. Bibcode:2010PNAS..107.2687J. doi:10.1073/pnas.0913572107. PMC 2823863. PMID 20133810.
