Diaminopimelic_acid

Diaminopimelic acid

Diaminopimelic acid

Chemical compound

Diaminopimelic acid (DAP) is an amino acid, representing an epsilon-carboxy derivative of lysine.

Quick Facts Names, Identifiers ...
Not to be confused with 2,3-Diaminopropionic acid.

DAP is a characteristic of certain cell walls[1] of some bacteria. DAP is often found in the peptide linkages of NAM-NAG chains that make up the cell wall of gram-negative bacteria. When provided, they exhibit normal growth. When in deficiency, they still grow but with the inability to make new cell wall peptidoglycan.

This is also the attachment point for Braun's lipoprotein.[2]

See also

Images

An alternate view of the DAP structure.

References

  1. [1]
    Brooks, George H.; Geo F. Brooks (2007). Jawetz, Melnick & Adelberg's medical microbiology. McGraw-Hill Medical. pp. 85. ISBN 978-0-07-147666-9.
  2. [2]
    Seltmann, Guntram; Holst, Otto (2002). The Bacterial Cell Wall. Berlin: Springer. pp. 81–82. ISBN 3-540-42608-6.


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