Dapiprazole

Dapiprazole
Clinical data
AHFS/Drugs.com	Consumer Drug Information
MedlinePlus	a601043
Pregnancy; category	B;
Routes of; administration	Topical (eye drops)
ATC code	S01EX02 (WHO) ;
Legal status
Legal status	In general: ℞ (Prescription only);
Pharmacokinetic data
Bioavailability	Negligible when administered topically
Identifiers
	IUPAC name 3-{2-[4-(2-methylphenyl)piperazin-1-yl]ethyl}-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,5-a]pyridine;
CAS Number	72822-12-9 ;
PubChem CID	3033538;
IUPHAR/BPS	7155;
DrugBank	DB00298 ;
ChemSpider	2298190 ;
UNII	5RNZ8GJO7K;
KEGG	D07775 ;
ChEBI	CHEBI:51066 ;
ChEMBL	ChEMBL1201216 ;
CompTox Dashboard (EPA)	DTXSID90223140 ;
Chemical and physical data
Formula	C19H27N5
Molar mass	325.460 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES n1nc(n2c1CCCC2)CCN4CCN(c3ccccc3C)CC4;
	InChI InChI=1S/C19H27N5/c1-16-6-2-3-7-17(16)23-14-12-22(13-15-23)11-9-19-21-20-18-8-4-5-10-24(18)19/h2-3,6-7H,4-5,8-15H2,1H3 ; Key:RFWZESUMWJKKRN-UHFFFAOYSA-N ;
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Dapiprazole

Chemical compound

Dapiprazole (brand name Rev-Eyes) is an alpha-1 blocker. It is used to reverse mydriasis after eye examination.^[1]

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[1] [1]
Doughty MJ, Lyle WM (May 1992). "A review of the clinical pharmacokinetics of pilocarpine, moxisylyte (thymoxamine), and dapiprazole in the reversal of diagnostic pupillary dilation". Optometry and Vision Science. 69 (5): 358–68. doi:10.1097/00006324-199205000-00005. PMID 1350669. S2CID 22781280.

[1]

Dapiprazole

References

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