DTX3L

DTX3L
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3PG6
Identifiers
Aliases	DTX3L, BBAP, deltex 3 like, E3 ubiquitin ligase, deltex E3 ubiquitin ligase 3L, RNF143
External IDs	OMIM: 613143 MGI: 2656973 HomoloGene: 51375 GeneCards: DTX3L
Gene location (Human)
Chr.	Chromosome 3 (human)
End	122,575,203 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	35,759,521 bp
RNA expression pattern
	Top expressed in
	pancreatic ductal cell; ; lower lobe of lung; ; pericardium; ; germinal epithelium; ; pylorus; ; human penis; ; palpebral conjunctiva; ; jejunal mucosa; ; synovial membrane; ; superficial temporal artery;
	Top expressed in
	jejunum; ; seminal vesicula; ; submandibular gland; ; blood; ; ileum; ; cervix; ; subcutaneous adipose tissue; ; thymus; ; left colon; ; spleen;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; metal ion binding; ubiquitin-protein transferase activity; transferase activity; enzyme inhibitor activity; enzyme activator activity; enzyme binding; histone binding; ubiquitin-like protein ligase binding; STAT family protein binding;
Cellular component	cytoplasm; nucleus; nucleoplasm; cytosol; early endosome; lysosome; lysosomal membrane; endosome; membrane; early endosome membrane; protein-containing complex;
Biological process	histone monoubiquitination; double-strand break repair; DNA repair; protein ubiquitination; cellular response to DNA damage stimulus; protein polyubiquitination; positive regulation of defense response to virus by host; endosome to lysosome transport; positive regulation of protein binding; histone H2A ubiquitination; histone H2B ubiquitination; positive regulation of chromatin binding; positive regulation of transcription, DNA-templated; negative regulation of ubiquitin-protein transferase activity; protein autoubiquitination; protein K48-linked ubiquitination; positive regulation of protein localization to nucleus; positive regulation of NAD+ ADP-ribosyltransferase activity; positive regulation of protein localization to early endosome; positive regulation of receptor catabolic process; positive regulation of double-strand break repair via nonhomologous end joining; immune system process; protein transport; innate immune response; defense response to virus; chromatin organization; ubiquitin-dependent protein catabolic process; Notch signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	151636
	209200
	ENSG00000163840
	ENSMUSG00000049502
	Q8TDB6
	Q3UIR3
	NM_138287
	NM_001013371
	NP_612144
	NP_001013389
	Wikidata
View/Edit Human	View/Edit Mouse

DTX3L

Protein-coding gene in the species Homo sapiens

Deltex E3 ubiquitin ligase 3L is a protein that in humans is encoded by the DTX3L gene. ^[5]

Quick Facts Available structures, PDB ...

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This article uses material from the Wikipedia article DTX3L, and is written by contributors. Text is available under a CC BY-SA 4.0 International License; additional terms may apply. Images, videos and audio are available under their respective licenses.

[refGRCh38Ensembl-1] [1]
GRCh38: Ensembl release 89: ENSG00000163840 – Ensembl, May 2017

[refGRCm38Ensembl-2] [2]
GRCm38: Ensembl release 89: ENSMUSG00000049502 – Ensembl, May 2017

[3] [3]
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] [4]
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] [5]
"Entrez Gene: Deltex E3 ubiquitin ligase 3L". Retrieved 2017-03-26.

[5]

[1]

[2]

[3]

[4]

DTX3L

DTX3L

Function

References

Further reading

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