Crosstown is an unincorporated settlement situated in Salem Township in Perry County, Missouri, United States, near the Mississippi River.

Crosstown was settled in 1840s as a farming community, but never had a name until a post office was established which was reportedly named for its crossroads location.^[3][4] The post office operated from 1886–1954 ^[5]

It is most notable for being devastated by an F4 tornado on September 22, 2006, although no one was killed.^[6]

On September 22, 2006, significant destruction and damage were caused by an F4 tornado.^[7]

• Tornado 2006 damage
• Tornado destruction
• Tornado destruction
• Tornado destruction
• Tornado destruction
• Tornado destruction
• Zion Lutheran rebuilt following 2006 tornado

Crosstown has three churches in the community. There is St. James Catholic Church, which was founded in 1890.^[8] The Baptist church is Bethlehem Baptist Church, which was destroyed by the tornado in 2006, except for the foundation. The church congregation decided to rebuild at the same location and consecrated their new church in 2007. The Lutheran church is Zion Lutheran Church of Crosstown.^[9] The tornado destroyed the roof and all the windows in the building. Miraculously, the Catholic Church had no real damage done except the stained glass windows all being broken.

• Old Earl Farrar General Store
• St. James Roman Catholic Church
• Zion Lutheran Church
• Bethlehem Baptist Church