Combination_antibiotic
A combination antibiotic is one in which two ingredients are added together for additional therapeutic effect.[1] One or both ingredients may be antibiotics.[1]
Antibiotic combinations are increasingly important because of antimicrobial resistance.[2] This means that individual antibiotics that used to be effective are no longer effective,[1] and because of the absence of new classes of antibiotic, they allow old antibiotics to be continue to be used.[2] In particular, they may be required to treat multiresistant organisms,[1][2] such as carbapenem-resistant Enterobacteriaceae.[3] Some combinations are more likely to result in successful treatment of an infection.[1]