Clobetasol_propionate
Clobetasol propionate
Medication
Clobetasol propionate is a corticosteroid used to treat skin conditions such as eczema, contact dermatitis, seborrheic dermatitis, and psoriasis.[3] It is applied to the skin as a cream, ointment, or shampoo.[3][4] Use should be short term and only if other weaker corticosteroids are not effective.[4] Use is not recommended in rosacea or perioral dermatitis.[3]
Common side effects include skin irritation, dry skin, redness, pimples, and telangiectasia.[3] Serious side effects may include adrenal suppression, allergic reactions, cellulitis, and Cushing's syndrome.[3] Use in pregnancy and breastfeeding is of unclear safety.[5] Clobetasol is believed to work by activating steroid receptors.[3]
Clobetasol propionate was patented in 1968 and came into medical use in 1978.[6] It is available as a generic medication.[4] In 2021, it was the 162nd most commonly prescribed medication in the United States, with more than 3 million prescriptions.[7][8]