Charles Wesley Weldon, QC (February 27, 1830 – January 12, 1896) was a Canadian lawyer and politician. He represented the City and County of St. John in the House of Commons of Canada from 1878 to 1891 as a Liberal member.

He was born in Richibucto, New Brunswick, the son of John Wesley Weldon and Frances Chandler Upham. He was educated at King's College in Windsor, Nova Scotia. He studied law in his father's office, was called to the bar in 1851 and set up practice in Saint John. In 1860, he married Annie Tucker. He was originally opposed to Confederation. In 1873, he was named Queen's Counsel. Weldon was defeated in the 1891 general election.