The Calle Mayor is a centric street in Madrid, Spain. Located in the Centro District, the Calle Mayor starts in the Puerta del Sol and ends at the cuesta de la Vega.^[1]

Created in the Middle Ages it originally connected the alcázar with the Puerta de Guadalajara (a disappeared wall gate).^[2] The Calle Mayor, that borders the Plaza Mayor to the North, became the main thoroughfare of the city in the Early Modern Period.^[3] The Calle Mayor was the place where the guilds of silversmiths and jewelers concentrated.^[4] In the 18th century, the street was divided in three sections with different names: Almudena (from the alcázar surroundings to the Plazuela de la Villa; Platería (from the plazuela de la Villa to the Puerta de Guadalajara), and Mayor (from the Puerta de Guadalajara to the Puerta del Sol).^[5][6]