CRD-BP
The mouse Coding Region Determinant-Binding Protein (CRD-BP) is an RNA-binding protein.[1] CRD-BP belongs to a family of RNA binding proteins that show close a relation to the chicken β-actin zipcode-binding protein ZBP1[1] and the human forms of the protein IMP-1, IMP-2 and IMP-3.[1][2][3] Because of their close relationship, CRD-BP and its orthologs are thought to share the same biochemical properties. Upon binding to its transcripts, CRD-BP plays a role in translation by stabilizing and localizing the transcripts in the cell.[3] Normal expression of CRD-BP has been seen in the early development of the embryo.[3] Conversely, CRD-BP expression in adult tissue is extremely low or completely absent.[4]