William Edwin Burwell (March 27, 1895 – June 11, 1973) was an American professional baseball player, manager and coach. Born in Jarbalo, Kansas, Burwell was a right-handed pitcher who stood 5 feet 11 inches (1.80 m) tall and weighed 175 pounds (79 kg).

Burwell won 239 minor league games during a 22-year playing career (1915–17, 1919–35, 1937–38). He pitched for all or parts of 12 straight seasons, between 1923 and 1934, for the Indianapolis Indians of the American Association.

In Major League Baseball, he appeared in 66 career games for the 1920–21 St. Louis Browns and four contests for the 1928 Pittsburgh Pirates. In his 70 MLB games, six as a starting pitcher, he won nine games and lost eight, with a 4.37 earned run average. He posted six saves and one complete game, allowing 253 hits and 79 bases on balls, with 49 strikeouts, in 2181⁄3 innings pitched.

He also fashioned a lengthy post-pitching career as a minor league manager (including two seasons, 1945–46, as skipper of the Indianapolis franchise) and Major League coach. He worked in the latter role for the Boston Red Sox (1944) and Pittsburgh Pirates (1947–48; 1958–62). While serving as pitching coach on Danny Murtaugh's staff, Burwell was a member of the Pirates' 1960 world championship team.

Burwell was acting manager of the Pirates for the final game of the 1947 season, after player-manager Billy Herman resigned with one game remaining.^[1] Under Burwell, the Pirates defeated the Cincinnati Reds, 7–0.^[1] He also was a longtime scout and roving minor league coach for the Pirates.

While working as pitching instructor in the Pirate organization in 1949, Burwell was instrumental to the development of pitcher Vern Law, then toiling for the Class B Davenport Pirates of the Illinois–Indiana–Iowa League. Burwell taught the 19-year-old Law how to change speeds and throw the change-up.^[1] Law — winner of the 1960 Cy Young Award as the top pitcher in the majors — later cited Burwell as the coach who most helped him during his time in the minor leagues.^[1]

Burwell died at age 78 in Ormond Beach, Florida, and is buried in nearby Daytona Beach.