Bendazac

Bendazac

Bendazac

Chemical compound


Bendazac (or bendazolic acid) is a nonsteroidal anti-inflammatory drug (NSAID) used for joint and muscular pain.[1]

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Synthesis

Principal action is inhibition of protein denaturation.

Bendazac synthesis: BE 699226; G. Palazzo, U.S. patent 3,470,194 (1967, 1969 both to Francesco Angelini).

Use of chloroacetamide in the alkylation step, followed by acid hydrolysis produces bendazac (instead of benzydamine).

See also


References

  1. Balfour JA, Clissold SP (April 1990). "Bendazac lysine. A review of its pharmacological properties and therapeutic potential in the management of cataracts". Drugs. 39 (4): 575–96. doi:10.2165/00003495-199039040-00007. PMID 2190795. S2CID 46956362.




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