Azatadine

Azatadine

Azatadine

Chemical compound

Azatadine (Optimine) is a first-generation antihistamine and anticholinergic drug that was synthesized in 1963 by Schering-Plough, a former American pharmaceutical company.[1][2]

Not to be confused with azetidine.
Quick Facts Clinical data, Trade names ...

It was patented in 1967.[3] It has been succeeded by both loratadine and desloratadine.[4]: 53  and marketing approvals have been widely withdrawn.[5][6][7][8]: 290 [9]

See also

References

  1. [1]
    Katelaris C (December 1990). "Comparative effects of loratadine and azatadine in the treatment of seasonal allergic rhinitis". Asian Pacific Journal of Allergy and Immunology. 8 (2): 103–7. PMID 1982614.
  2. [2]
    Small P, Barrett D, Biskin N (February 1990). "Effects of azatadine, terfenadine, and astemizole on allergen-induced nasal provocation". Annals of Allergy. 64 (2 Pt 1): 129–31. PMID 1968324.
  3. [3]
    US 3326924, Villani FJ, Caldwell W, "Azatadine", issued 1967
  4. [4]
    Horak F (2010). "Antialergic and Vasoactive Drugs for Allergic Rhinitis. Chapter 4". In Pawankar R, Holgate ST, Rosenwasser LJ (eds.). Allergy Frontiers:Therapy and Prevention. Vol. 5. Springer Science & Business Media. ISBN 9784431993629.
  5. [5]
    "Azatadine". Drugs.com.
  6. [6]
    Food and Drug Administration (2005). "Docket No.2005N-0058: Hospira, Inc. et al.; Withdrawal of Approval of 76 New Drug Applications and 60 Abbreviated New Drug Applications". Federal Register 70 FR 10651.
  7. [7]
    Food and Drug Administration (2007). "Docket No. 2004P-0262: Withdrawal of Approval of 128 Suitability Petitions". Federal Register 72 FR 8184.
  8. [8]
    "Consolidated List of Products Whose Consumption and/or Sale Have Been Banned, Withdrawn, Severely Restricted or not Approved by Governments Twelfth Issue: Pharmaceuticals" (PDF). Department of Economic and Social Affairs of the United Nations Secretariat. New York: United Nations. 2005.
  9. [9]
    "OGD Suitability Tracking Report (Sorted by Drug Name)". FDA.


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