Arens–van_Dorp_synthesis
The Arens–van Dorp synthesis is a name reaction in organic chemistry.[1] It describes the addition of lithiated ethoxyacetylenes to ketones to give propargyl alcohols, which can undergo further reaction to form α,β-unsaturated aldehydes,[2] or esters.[3] There is also a variation of this reaction called the Isler modification, where the acetylide anion is generated in situ from β-chlorovinyl ether using lithium amide.[4][5]