Alphapolyomavirus

<i>Alphapolyomavirus</i>

Alphapolyomavirus

Genus of virus

Alphapolyomavirus is one of eight genera of non-enveloped dsDNA viruses in the polyomaviridae family.[1][2] Member viruses primarily infect humans and other mammals.[3] Transmission of the virus in humans is primarily spread via direct contact with parents or other high-contact individuals as children.[4][5]

Quick Facts Alphapolyomavirus, Virus classification ...

The primary alphapolyomavirus that is of clinical significance to humans is Merkel cell polyomavirus (Human polyomavirus 5, MCV, or MCPyV). The apparent oncogenicity of MCPyV[6] similar to other cancer-causing viruses such as HPV, Epstein-Barr virus, and Hepatitis C virus[7] is a main area of research for the scientific community.

References

  1. [1]
    taxonomy. "Taxonomy browser (Polyomaviridae)". www.ncbi.nlm.nih.gov. Retrieved 2024-03-19.
  2. [2]
    "Alphapolyomavirus ~ ViralZone". viralzone.expasy.org. Retrieved 2024-03-19.
  3. [3]
    "Genus: Alphapolyomavirus | ICTV". ictv.global. Retrieved 2024-03-19.
  4. [4]
    Kunitake, T; Kitamura, T; Guo, J; Taguchi, F; Kawabe, K; Yogo, Y (Jun 1995). "Parent-to-child transmission is relatively common in the spread of the human polyomavirus JC virus". Journal of Clinical Microbiology. 33 (6): 1448–1451. doi:10.1128/jcm.33.6.1448-1451.1995. ISSN 0095-1137. PMC 228193. PMID 7650165.
  5. [5]
    Boothpur, Raghavender; Brennan, Daniel C. (Apr 2010). "Human Polyoma Viruses and Disease with Emphasis on Clinical BK and JC". Journal of Clinical Virology. 47 (4): 306–312. doi:10.1016/j.jcv.2009.12.006. ISSN 1386-6532. PMC 3774018. PMID 20060360.
  6. [6]
    Spurgeon, Megan E.; Lambert, Paul F. (2013-01-05). "Merkel Cell Polyomavirus: A Newly Discovered Human Virus with Oncogenic Potential". Virology. 435 (1): 118–130. doi:10.1016/j.virol.2012.09.029. ISSN 0042-6822. PMC 3522868. PMID 23217622.
  7. [7]
    "Gale – Product Login". galeapps.gale.com. Retrieved 2024-03-19.
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