Adipostatin_A

Adipostatin A

Adipostatin A

Chemical compound


Adipostatin A is an alkylresorcinol, a type of phenolic lipids composed of long aliphatic chains and phenolic rings. Chemically, it is similar in structure to urushiol, the irritant found in poison ivy.

Quick Facts Names, Identifiers ...

Adipostatin A can be found in Ginkgo biloba fruits as well as in Streptomyces cyaneus.[1] It is also found in cashew nutshell liquid (Anacardium occidentale), in Anacardium othonianum and in Ardisia elliptica.[2]

It is an inhibitor of glycerol-3-phosphate dehydrogenase.[3]


References

  1. Tanaka, A; Arai, Y; Kim, SN; Ham, J; Usuki, T (2011). "Synthesis and biological evaluation of bilobol and adipostatin A". Journal of Asian Natural Products Research. 13 (4): 290–6. doi:10.1080/10286020.2011.554828. PMID 21462031. S2CID 25305504.
  2. Koh Hwee Ling, Chua Tung Kian, and Tan Chay Hoon. "A Guide to Medicinal Plants: An Illustrated, Scientific and Medicinal Approach", p. 14. World Scientific Publishing 2009, ISBN 981-283-709-4. Preview available at Google Books
  3. Tsuge, N; Mizokami, M; Imai, S; Shimazu, A; Seto, H (1992). "Adipostatins a and B, new inhibitors of glycerol-3-phosphate dehydrogenase". The Journal of Antibiotics. 45 (6): 886–91. doi:10.7164/antibiotics.45.886. PMID 1500355.



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