Acrodermatitis_chronica_atrophicans
Acrodermatitis chronica atrophicans
Medical condition
Acrodermatitis chronica atrophicans (ACA) is a skin rash indicative of the third or late stage of European Lyme borreliosis.
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ACA is a dermatological condition that takes a chronically progressive course and finally leads to a widespread atrophy of the skin. Involvement of the peripheral nervous system is often observed, specifically polyneuropathy.
This progressive skin process is due to the effect of continuing active infection with the spirochete Borrelia afzelii, which is the predominant pathophysiology.[3] B. afzelii may not be the exclusive etiologic agent of ACA; Borrelia garinii has also been detected.[citation needed]