ADCY4

ADCY4

ADCY4

Protein-coding gene in the species Homo sapiens

Adenylyl cyclase type 4 is an enzyme that in humans is encoded by the ADCY4 gene.[5][6]

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Function

This gene encodes a member of the family of adenylyl cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylyl cyclase 4, along with adenylyl cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylyl cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals.[6]

References

  1. [1]
    ENSG00000284814 GRCh38: Ensembl release 89: ENSG00000129467, ENSG00000284814 – Ensembl, May 2017
  2. [2]
    GRCm38: Ensembl release 89: ENSMUSG00000022220 – Ensembl, May 2017
  3. [3]
    "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. [4]
    "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. [5]
    Edelhoff S, Villacres EC, Storm DR, Disteche CM (Jul 1995). "Mapping of adenylyl cyclase genes type I, II, III, IV, V, and VI in mouse". Mamm Genome. 6 (2): 111–3. doi:10.1007/BF00303253. PMID 7766992. S2CID 27766000.
  6. [6]
    "Entrez Gene: ADCY4 adenylate cyclase 4".

Further reading


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