This is a list of notable events in Latin music (i.e., music from the Spanish- and Portuguese-speaking areas Latin America, Latin Europe, and the United States) that took place in 1999.

• February 24 — The 41st Annual Grammy Awards are held at the Shrine Auditorium in Los Angeles.:^[1]
  • Vuelve by Ricky Martin wins the award for Best Latin Pop Performance.
  • Contra la Corriente by Marc Anthony wins the award for Best Tropical Latin Performance.
  • Los Super Seven's self-titled album wins the award for Best Mexican-American Music Performance
  • Sueños Líquidos by Maná wins the award for Best Latin Rock/Alternative Performance.
  • Said and Done by Flaco Jiménez wins the award for Best Tejano Music Performance.
  • Hot House by Arturo Sandoval wins the award for Best Latin Jazz Performance.
• May 6 — The 11th Annual Lo Nuestro Awards are held at the James L. Knight Center in Miami, Florida. Puerto Rican American singer Elvis Crespo is the most awarded artist with five wins.^[2]
• April 20 to April 22 — Billboard holds its 10th Annual Latin Music Conference at the Fontainebleau Hotel in Miami, Florida.^[3]
  • In the same week, Billboard holds its 6th Annual Latin Music Awards on April 22. Puerto Rican American singer Elvis Crespo is the most awarded artist with four wins. Spanish singer Rocío Dúrcal is inducted into the Billboard Latin Music Hall of Fame.
• November 20 — The Latin Academy of Recording Arts & Sciences announces that the inaugural Latin Grammy Awards would held in 2001. The new music awards would encompass music Latin America, Spain, Portugal, and the United States. It would later be pushed forward to September 2000.^[4]
• December 26 — The Recording Industry Association of America (RIAA) reports a 12% growth on the Latin music market in the United States compared to 1998. This gives Latin music a 4.9% share of the total music market. The report does not include sales of albums done by English-speaking Latino artists as the RIAA only considers an album to be "Latin" if 51% or more of its content is recorded in Spanish.^[5]

• List of number-one albums of 1999 (Spain)
• List of number-one singles of 1999 (Spain)
• List of number-one Billboard Top Latin Albums of 1999
• List of number-one Billboard Hot Latin Tracks of 1999

• 1999 Premio Lo Nuestro
• 1999 Billboard Latin Music Awards
• 1999 Tejano Music Awards

• January 5 – Miguelito, Puerto Rican reggaeton singer
• January 11 – Christian Nodal, Mexican ranchera singer
• June 27 – Aitana, Spanish pop singer
• August 7 – Mariah Angeliq, American reggaeton singer
• August 13 – Giulia Be, Brazilian pop singer

• January 14 – Sabina Olmos, 85, Argentine tango singer and actress
• February 17 – Tania, 105, Spanish-Argentine tango singer and actress
• March 19 – Juanita Reina, 73, Spanish actress and singer of copla music
• September 14 – Eddy Gaytán [es], 70, Argentine-Cuban musician
• October 6 – Amália Rodrigues, 79, Portuguese singer known worldwide as the "Queen of Fado".