Week 1: vs. Tampa Bay Buccaneers

The Lions hosted the Tampa Bay Buccaneers in the season and home opener. The Buccaneers received the opening kickoff and took their first drive 4 plays and 71 yards into the endzone on a Vinny Testaverde 54-yard pass to Ron Hall. The Lions got the ball with a chance to respond on their own 20-yard line. After an incomplete pass, Rodney Peete completed a pass to Robert Clark four times in a row including the 15-yard touchdown pass to tie the game at 7–7. The Buccaneers took their next drive into Lions' territory when a Gary Anderson rush for 2 yards turned into a fumble that was recovered by the Lions. At their own 27, the Lions moved downfield with multiple 10+ yard passes and Barry Sanders rushes to cap off the scoring drive with a Sanders 1-yard rushing touchdown to put the Lions up 14–7. The Bucs' took their responding drive into the second quarter. Testaverde capped the drive off with a 8-yard pass into the end zone to tie the game 14–14. On the Lions next possession, an overthrown Peete pass intended for Clark fell into the hands of a Buccaneers defender. The Bucs took three plays to make it into the endzone with a Testaverde 19-yard pass to Anderson. The teams punted on each of their drives to end the first half.^[18]

The Lions received the second half kickoff, but fumbled it away on second down, turning it over. The Buccaneers quickly scored with aReggie Cobb 2-yard rushing touchdown to put the Buccaneers up 28–14. The Lions punted on their next drive, with the Buccaneers taking over on the Lions 47. The Bucs' got down to the Lions 25-yard line, but a Testaverde pass that went through the hands of Mark Carrier was intercepted which was returned 48-yard to the Bucs 32-yard line. The Lions moved the ball to the Bucs' 8-yard line. On 2nd and 7, Peete faked the handoff to Sanders and ran around to the right into the end zone for the 8-yard touchdown. However, upon review, the play was overturned. The Lions converted a 3rd and 1 on the 2 with a Sanders 1-yard rush. On 1st down from the 1, Peete fumbled the ball attempting a QB sneak which was turned over for a touchback. The Bucs took their new possession into the fourth quarter, settling for a 22-yard field goal by Steve Christie. On the Lions next drive, a 24-yard Sanders rush and a Bob Gagliano pass to Clark for 21 set up the 16-yard touchdown pass from Gagliano to Clark. The Lions attempted an onside kick, successfully recovering it with 5:28 left in the game. On the first play of their new drive, Gagliano threw an interception that was returned 62-yards for the touchdown. On the Lions first play after the turnover, the Lions turned the ball over again on a fumble. The Lions had one more drive to produce points, but a Gagliano interception leading to the two-minute warning sealed the 21–38 loss for the Lions.^[18]

Week 2: vs. Atlanta Falcons

In Week 2, the Lions hosted the Atlanta Falcons. The Lions received the opening kickoff. After a delay of game, Rodney Peete found Jason Phillips for 15 yards on 3rd and 16, electing to punt on the ensuing 4th and 1. On the Falcons' first drive, they got down to the 50-yard line on 3rd and 6, but were sacked and had to punt. On the first play of the Lions' new drive, Peete scrambled right and found Phillips for 29 yards. On the next play, Peete passed to Richard Johnson for a gain of 13 yards with an Atlanta 15-yard personal foul penalty bringing the Lions to the Falcons 15-yard line. A Barry Sanders rush brought them three before Peete found Terry Greer in the end zone to put the Lions up 7–0. After a three-and-out from both teams, the Falcons went from their own 27 to the Lions 13 with a Chris Miller 60-yard pass to Michael Haynes. After an incompletion and a three-yard rush, Miller found Andre Rison in the end zone on 3rd and 7 to tie it at 7–7. The Lions brought their responding scoring drive into the second quarter. They crossed midfield with a Peete pass to Robert Clark that went for 23-yards. They slowly inched down Falcons territory, converting a 3rd and 5 from the Falcons 13 with a Sanders 12-yard run that brought them to the goal-line. After Sanders was brought down 4 yards behind the line of scrimmage, Peete found Johnson in the end zone to go up 14–7. The teams exchanged punts along with a Peete intercepted followed up by an Atlanta punt. The Lions got possession with 1:14 left in the second half following a bad 24-yard punt that set them up at the Falcons 36. It took the Lions 54 seconds to reach the endzone with a Sanders 17-yard rushing touchdown to put the halftime score at 21–7.^[19]

The Falcons received the opening kickoff to start the second half. The Falcons, beginning at their own 37-yard line, moved into Lions territory with a Miller pass to Keith Jones for 11 yards. The Falcons got down to the Lions 3 on 2nd down and scored on a Steve Broussard 3-yard rushing touchdown to put the Falcons within 7 at 14–21. After two punts for each team, Peete threw an interception on 2nd and 20 to bring the Falcons' new drive into the fourth quarter. The Falcons looked poised to score when the team got down to the Lions 13-yard line. However, Miller fumbled the snap which was recovered by Detroit. After a total of four punts, the Lions drained the remaining clock with help from a Bob Gagliano 22-yard rush to bring up the final score of 21–14.^[19]

Week 3: at Tampa Bay Buccaneers

Week 12: vs. Denver Broncos