Events from the year 1822 in the United States.

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See also:	History of the United States (1789–1849) Timeline of United States history (1820–1859) List of years in the United States

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• March 30 – The U.S. merges East Florida with part of West Florida to form the Florida Territory.
• July 1–3 – U.S. House of Representatives elections begin in Louisiana and continue until the last elections are held in North Carolina on August 14, 1823.
• July 2 – Denmark Vesey is hanged for plotting a slave rebellion in Charleston, South Carolina.
• July 4 – A 24th star is added to the flag of the United States, representing Missouri which had been admitted on August 10, 1821.
• August 22 – The English ship Orion lands at Yerba Buena, modern-day San Francisco, under the command of William A. Richardson.
• November 9 – Action of 9 November 1822: USS Alligator (1820) engages three pirate schooners off the coast of Cuba as part of the West Indies anti-piracy operations of the U.S.
• November 23 – The USS Alligator wrecks on Carysford Reef off the coast of Florida.^[1]
• December 5 – Edward Coles is sworn in as the second governor of Illinois, replacing Shadrach Bond.

• February 4 – Edward Fitzgerald Beale, U.S. Navy lieutenant and explorer (died 1893)
• February 13 – James B. Beck, Scottish-born U.S. Senator from Kentucky from 1877 to 1890 (died 1890)
• c. March – Harriet Tubman, born Araminta Ross, African-American abolitionist, humanitarian, and Union spy during the American Civil War (died 1913)
• March 12 – Thomas Buchanan Read, poet and portrait painter (died 1872)
• March 16 – John Pope, career United States Army officer and Union general in the American Civil War (died 1892)
• April 3 – Edward Everett Hale, writer (died 1909)
• April 26 – Frederick Law Olmsted, landscape architect (died 1903)
• April 27 – Ulysses S. Grant, 18th president of the United States from 1869 to 1877 (died 1885)
• May 18 – Mathew B. Brady, pioneer photographer (died 1896)
• June 10 –
  • John Jacob Astor III, businessman (died 1890)
  • Lydia White Shattuck, botanist (died 1889)
• July 21 – Alexander H. Jones, Congressional Representative from North Carolina. (died 1901)
• July 25 – Andrew Bryson, admiral (died 1892)
• August 15
  • James E. Bailey, U.S. Senator from Tennessee from 1877 to 1881 (died 1885)
  • Virginia Eliza Clemm Poe, wife of Edgar Allan Poe (died 1847)
• August 27 – William Hayden English, politician (died 1896)
• September 11 – Francis S. Thayer, merchant and politician (died 1880)
• September 16 – Charles Crocker, financiers (died 1888)
• September 17 – Cornelius Cole, U.S. Senator from California from 1867 to 1873 (died 1924)
• September 19 – Joseph R. West, U.S. Senator from Louisiana from 1871 to 1877 (died 1898)
• September 20 – Elizabeth Smith Miller, women's rights campaigner (died 1911)
• October 4 – Rutherford B. Hayes, 19th president of the United States from 1877 to 1881 (died 1893)
• Undated – Red Cloud (Maȟpíya Lúta), Oglala Lakota chief (died 1909)

• April 8 – James Long, U.S. Filibuster, founder of the Long Republic - the first "Republic of Texas". Shot by a prison guard in Mexico City, Mexico (born 1793).
• May 6 – Charles Peale Polk, portrait painter (born 1767)
• May 8 – John Stark, major general in the Continental Army during the American Revolution (born 1728)
• July 2 – Denmark Vesey, African American leader, hanged (born c.1767)
• August 28 – William Logan, U.S. Senator from Kentucky from 1819 to 1820 (born 1776)
• October 31 – Jared Ingersoll, U.S. presidential candidate (born 1749)

• Timeline of United States history (1820–1859)