Gold Award for Best Actress in a Lead Role is an award given as part of its annual Gold Awards for TV serials.

The award was first awarded in 2007 under the title Best Actress in a Lead Role. A special award called Best Actor – Critics or Best Actor – Jury is also awarded occasionally since 2008, whose winner was selected by the jury of critics assigned to the function.

The jury award was awarded without prior nominations until 2010. Since then, the jury award is also awarded with prior nominations just like the original award which is now called Best Actress – Popular.

• Divyanka Tripathi with four awards has the most wins, followed by Ankita Lokhande, Deepika Singh and Shraddha Arya with two wins each.
• Tripathi also holds the most nominations with six.
• Divyanka Tripathi holds the record of three wins for same role (Yeh Hai Mohobatein) under Best Actress category
• Rashami Desai holds most nominations in three different categories for same role (Uttaran), that is, for Best Actress (Popular), Best Actress (Critics) and Best Actress in a negative role (Popular), out of which Desai won the latter two.
• There have been four ties: between Ankita Lokhande and Mahi Vijj in 2011, Divyanka Tripathi and Mouni Roy in 2016, Sriti Jha and Shraddha Arya in 2018, and Shraddha Arya and Shivangi Joshi in 2019.

• 6 Nominations: Divyanka Tripathi
• 5 Nominations: Sriti Jha
• 4 Nominations: Deepika Singh
• 3 Nominations: Hina Khan, Shweta Tiwari, Shivangi Joshi, Ankita Lokhande, Kratika Sengar
• 2 Nominations: Pooja Gor, Giaa Manek, Avika Gor, Sakshi Tanwar, Drashti Dhami, Sanaya Irani, Devoleena Bhattacharjee, Dipika Kakar, Mouni Roy, Surbhi Chandna, Shraddha Arya, Rubina Dilaik