ZFHX3

ZFHX3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2DA1, 2DA2, 2DA3
Identifiers
Aliases	ZFHX3, ATBF1, ATBT, ZNF927, zinc finger homeobox 3
External IDs	OMIM: 104155; MGI: 99948; HomoloGene: 21366; GeneCards: ZFHX3; OMA:ZFHX3 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	73,891,871 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	109,688,262 bp
RNA expression pattern
	Top expressed in
	saphenous vein; ; synovial joint; ; pericardium; ; urethra; ; trigeminal ganglion; ; spinal ganglia; ; lower lobe of lung; ; seminal vesicula; ; human penis; ; renal medulla;
	Top expressed in
	ascending aorta; ; aortic valve; ; external carotid artery; ; lacrimal gland; ; internal carotid artery; ; ciliary body; ; superior cervical ganglion; ; stria vascularis; ; conjunctival fornix; ; medial dorsal nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; sequence-specific DNA binding; DNA-binding transcription factor activity; zinc ion binding; metal ion binding; core promoter sequence-specific DNA binding; protein binding; nucleic acid binding; enzyme binding; transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	cytoplasm; nuclear body; transcription regulator complex; nucleus; nucleoplasm;
Biological process	negative regulation of myoblast differentiation; regulation of transcription, DNA-templated; regulation of locomotor rhythm; muscle organ development; transcription by RNA polymerase II; circadian regulation of gene expression; transcription, DNA-templated; positive regulation of transcription, DNA-templated; positive regulation of myoblast differentiation; negative regulation of transcription, DNA-templated; response to transforming growth factor beta; negative regulation of transcription by RNA polymerase II; brain development; regulation of neuron differentiation; positive regulation of cell adhesion; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	463
	11906
	ENSG00000140836
	ENSMUSG00000038872
	Q15911
	Q61329
	NM_001164766; NM_006885
	NM_007496
	NP_001158238; NP_008816
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

ATBF1

Protein-coding gene in humans

Zinc finger homeobox protein 3 is a protein that in humans is encoded by the ZFHX3 gene.^[5]^[6]^[7]

Quick Facts ZFHX3, Available structures ...

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This article uses material from the Wikipedia article ZFHX3, and is written by contributors. Text is available under a CC BY-SA 4.0 International License; additional terms may apply. Images, videos and audio are available under their respective licenses.

[refGRCh38Ensembl-1] [1]
GRCh38: Ensembl release 89: ENSG00000140836 – Ensembl, May 2017

[refGRCm38Ensembl-2] [2]
GRCm38: Ensembl release 89: ENSMUSG00000038872 – Ensembl, May 2017

[3] [3]
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] [4]
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1719379-5] [5]
Morinaga T, Yasuda H, Hashimoto T, Higashio K, Tamaoki T (Dec 1991). "A human alpha-fetoprotein enhancer-binding protein, ATBF1, contains four homeodomains and seventeen zinc fingers". Mol Cell Biol. 11 (12): 6041–9. doi:10.1128/MCB.11.12.6041. PMC 361769. PMID 1719379.

[pmid7592926-6] [6]
Miura Y, Tam T, Ido A, Morinaga T, Miki T, Hashimoto T, Tamaoki T (Dec 1995). "Cloning and characterization of an ATBF1 isoform that expresses in a neuronal differentiation-dependent manner". J Biol Chem. 270 (45): 26840–8. doi:10.1074/jbc.270.45.26840. PMID 7592926.

[entrez-7] [7]
"Entrez Gene: ATBF1 AT-binding transcription factor 1".

[5]

[6]

[7]

[1]

[2]

[3]

[4]

ZFHX3

ATBF1

References

Further reading

External links

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