Wilbur Edwin Murdoch (March 14, 1875 – October 29, 1941) was a backup outfielder in Major League Baseball who played briefly for the St. Louis Cardinals during the 1908 season. He threw right-handed. His batting side is unknown.

A native of Avon, New York, Murdoch was 33 years old when he entered the majors with the Cardinals. In a 27-game career, he was a .258 hitter (16-for-62) with five runs and five RBI, including three doubles and four stolen bases without home runs.

Murdoch died in Los Angeles, California, at the age of 66.

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