W-hydroxydecanoate_dehydrogenase

Omega-hydroxydecanoate dehydrogenase

Omega-hydroxydecanoate dehydrogenase

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In enzymology, an omega-hydroxydecanoate dehydrogenase (EC 1.1.1.66) is an enzyme that catalyzes the chemical reaction

10-hydroxydecanoate + NAD+ ⇌ 10-oxodecanoate + NADH + H+
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Thus, the two substrates of this enzyme are 10-hydroxydecanoate and NAD+, whereas its 3 products are 10-oxodecanoate, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 10-hydroxydecanoate:NAD+ 10-oxidoreductase.

References

    • Kamei S, Wakabayashi K, Shimazono M (1964). "Studies on ω-Oxidation of Fatty Acids in vitro: II. ω-Hydroxy Fatty Acid: NAD Oxidoreductase". J. Biochem. 56: 72–76. PMID 14202238.
    • Mitz MA; Henrikson RL (1961). "Omega hydroxy fatty acid dehydrogenase". Biochim. Biophys. Acta. 46: 45–50. doi:10.1016/0006-3002(61)90644-8. PMID 13771448.


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