VSIG4

V-set and immunoglobulin domain containing 4

V-set and immunoglobulin domain containing 4

Protein-coding gene in the species Homo sapiens

V-set and immunoglobulin domain containing 4 is a protein that in humans is encoded by the VSIG4 gene.[5]

Quick Facts VSIG4, Available structures ...

Function

This gene encodes a v-set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins. The encoded protein may be a negative regulator of T-cell responses. This protein is also a receptor for the complement component 3 fragments C3b and iC3b. Alternate splicing results in multiple transcript variants.

References

  1. [1]
    GRCh38: Ensembl release 89: ENSG00000155659 – Ensembl, May 2017
  2. [2]
    GRCm38: Ensembl release 89: ENSMUSG00000044206 – Ensembl, May 2017
  3. [3]
    "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. [4]
    "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. [5]
    "Entrez Gene: V-set and immunoglobulin domain containing 4". Retrieved 2016-06-13.

Further reading


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