The United States ambassador to Sweden (Swedish: Förenta Staternas ambassadör i Sverige) serves as the official diplomatic representative of the United States to the King and the Government of the Kingdom of Sweden. Diplomatic relations between Sweden and the United States began with the signing of the Treaty of Amity and Commerce in 1783. Sweden received its first U.S. resident minister in 1814, but in 1818, the senior U.S. diplomat again became the chargé d'affaires. In 1854, the senior American diplomat in Sweden again became the minister resident. From 1814 to 1905 the United States Chief of Mission in Sweden also represented United States interests with respect to Norway, as Norway was aligned with Sweden during this period in the Union between Sweden and Norway.

The contemporary tendency of American presidents is to appoint fundraisers or prominent campaign supporters to the ambassador's post in Sweden, rather than promoting career members of the United States Foreign Service. The current ambassador is Erik Ramanathan, who presented his credentials on January 20, 2022.

Since the 1930s, the ambassador is resident in the ambassadorial residence, Villa Åkerlund, of the United States Embassy in Diplomatstaden, Stockholm.