Sulfoacetaldehyde_dehydrogenase_(acylating)

Sulfoacetaldehyde dehydrogenase (acylating)

Sulfoacetaldehyde dehydrogenase (acylating)

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Sulfoacetaldehyde dehydrogenase (acylating) (EC 1.2.1.81, SauS) is an enzyme with systematic name 2-sulfoacetaldehyde:NADP+ oxidoreductase (CoA-acetylating).[1] This enzyme catalyses the following chemical reaction

2-sulfoacetaldehyde + CoA + NADP+ sulfoacetyl-CoA + NADPH + H+
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The enzyme is involved in degradation of sulfoacetate.

References

  1. [1]
    Weinitschke S, Hollemeyer K, Kusian B, Bowien B, Smits TH, Cook AM (November 2010). "Sulfoacetate is degraded via a novel pathway involving sulfoacetyl-CoA and sulfoacetaldehyde in Cupriavidus necator H16". The Journal of Biological Chemistry. 285 (46): 35249–54. doi:10.1074/jbc.M110.127043. PMC 2975148. PMID 20693281.
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