Sidney High School is a comprehensive, college-prep oriented public high school in Sidney, Ohio, which is located 40 miles (64 km) north of Dayton, Ohio, on Interstate 75. It is the only public high school in the Sidney City Schools district.

Sidney High School average enrollment is approximately 1,000, with approximately 200 students attending the Upper Valley Career Center in Piqua, OH. The average graduating class size is approximately 250 students.

Sidney City Schools offers more than 70 extracurricular activities for students from 6th grade on. Sports include: football; boys & girls soccer; boys & girls basketball; boys baseball; girls fastpitch; boys & girls tennis; co-ed track; co-ed bowling; co-ed swimming; co-ed cross country; girls volleyball; co-ed wrestling; weight lifting; cheerleading; marching band; and golf. Clubs include: Academia, Mock Trial, Breakfast Club, Key Club, Art Club, FFA, FCCLA; Debate Club; Environthon; German Club; Muse Machine; SADD; Student Government; National Honor Society; DECA; and Intramural Athletics.

Sidney High School is a long time member of the Miami Valley League (MVL). The Yellow Jacket's primary rival is Piqua High School.

• Warren Davidson, congressman (1989)
• Paul Lauterbur, chemist and Nobel Laureate (1947)
• Lois Lenski, writer (1911)

Sidney City Schools has a Hall of Honor which recognizes other notable alumni. More than 100 members make up the Sidney High School Hall of Honor, which was established in 1994.