The Saturn Award for Best Science Fiction Film is one of the Saturn Awards that has been presented annually since 1972 by Academy of Science Fiction, Fantasy and Horror Films to the best film in the science fiction genre of the previous year.

In the list below, winners are listed first in bold, followed by the other nominees. The number of the ceremony (1st, 2nd, etc.) appears in parentheses after the awards year, linked to the article (if any) on that ceremony.

• Science fiction film

• Official website
• Internet Movie Database: 1st, 2nd, 3rd, 4th, 5th, 6th, 7th, 8th, 9th, 10th, 11th, 12th, 13th, 14th, 15th, 16th, 17th, 18th, 19th, 20th, 21st, 22nd, 23rd, 24th, 25th, 26th, 27th, 28th, 29th, 30th, 31st, 32nd, 33rd, 34th, 35th, 36th, 37th, 38th, 39th, 40th, 41st, 42nd, 43rd