SLC7A3
Cationic amino acid transporter 3
Protein found in humans
Cationic amino acid transporter 3 is a protein that in humans is encoded by the SLC7A3 gene.[5][6]
Quick Facts SLC7A3, Identifiers ...
| SLC7A3 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Aliases | SLC7A3, ATRC3, CAT-3, CAT3, solute carrier family 7 member 3 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 300443; MGI: 1100521; HomoloGene: 56382; GeneCards: SLC7A3; OMA:SLC7A3 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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SLC7A3 is a member of the system y+ family of transporters characterized by sodium-independent transport of cationic amino acids.[supplied by OMIM][6]
- "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- Vekony N, Wolf S, Boissel JP, Gnauert K, Closs EI (Oct 2001). "Human cationic amino acid transporter hCAT-3 is preferentially expressed in peripheral tissues". Biochemistry. 40 (41): 12387–94. doi:10.1021/bi011345c. PMID 11591158.
- Hosokawa H, Sawamura T, Kobayashi S, et al. (1997). "Cloning and characterization of a brain-specific cationic amino acid transporter". J. Biol. Chem. 272 (13): 8717–22. doi:10.1074/jbc.272.13.8717. PMID 9079705.
- Ito K, Groudine M (1997). "A new member of the cationic amino acid transporter family is preferentially expressed in adult mouse brain". J. Biol. Chem. 272 (42): 26780–6. doi:10.1074/jbc.272.42.26780. PMID 9334265.
- Hosokawa H, Ninomiya H, Sawamura T, et al. (1999). "Neuron-specific expression of cationic amino acid transporter 3 in the adult rat brain". Brain Res. 838 (1–2): 158–65. doi:10.1016/S0006-8993(99)01686-8. PMID 10446328. S2CID 33405664.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Gilles W, Vulcu SD, Liewald JF, et al. (2005). "Monovalent cation conductance in Xenopus laevis oocytes expressing hCAT-3". Biochim. Biophys. Acta. 1668 (2): 234–9. doi:10.1016/j.bbamem.2004.12.011. PMID 15737334.
- Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
- Rotmann A, Vékony N, Gassner D, et al. (2006). "Activation of classical protein kinase C reduces the expression of human cationic amino acid transporter 3 (hCAT-3) in the plasma membrane". Biochem. J. 395 (1): 117–23. doi:10.1042/BJ20051558. PMC 1409692. PMID 16332251.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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