SF2 may refer to:

• SF zwei (Schweizer Fernsehen zwei), a Swiss television channel broadcasting in German
• Fahlin SF-2 Plymocoupe an experimental aircraft built by Ole Fahlin
• SoundFont 2, a file format for audio samples and associated data for use in musical synthesis
• ASF/SF2, a protein
• Sulfur difluoride, a chemical compound
• A kind of glass fabricated by Schott.
• SF2 (Scuba Force 2), an ECCR

• SaGa Frontier 2
• Secret Files 2: Puritas Cordis
• Shadow Fight 2
• Shining Force II
• Star Fox 2
• Street Fighter II
• Syphon Filter 2

This disambiguation page lists articles associated with the same title formed as a letter–number combination.
If an internal link led you here, you may wish to change the link to point directly to the intended article.