SEPT1

SEPTIN1

SEPTIN1

Protein-coding gene in the species Homo sapiens

Septin-1 is a protein that in humans is encoded by the SEPTIN1 gene.[5][6] It was renamed from SEPT1 to avoid problems where Microsoft Excel would auto-correct the gene name to the date September 1.[7]

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Function

This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. This gene encodes a protein associated with the tau-based paired helical filament core, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease.[6]

References

  1. [1]
    GRCh38: Ensembl release 89: ENSG00000180096 – Ensembl, May 2017
  2. [2]
    GRCm38: Ensembl release 89: ENSMUSG00000000486 – Ensembl, May 2017
  3. [3]
    "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. [4]
    "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. [5]
    Mori T, Miura K, Fujiwara T, Shin S, Inazawa J, Nakamura Y (Sep 1996). "Isolation and mapping of a human gene (DIFF6) homologous to yeast CDC3, CDC10, CDC11, and CDC12, and mouse Diff6". Cytogenetics and Cell Genetics. 73 (3): 224–7. doi:10.1159/000134343. PMID 8697812.
  6. [6]
    "Entrez Gene: SEPT1 septin 1".
  7. [7]
    Vincent J (6 August 2020). "Scientists rename human genes to stop Microsoft Excel from misreading them as dates". the Verge. Retrieved 2022-10-24.

Further reading

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