Recaldent
Amorphous calcium phosphate (ACP) is a glassy solid that is formed from the chemical decomposition of a mixture of dissolved phosphate and calcium salts (e.g. (NH4)2HPO4 + Ca(NO3)2). The resulting amorphous mixture consists mostly of calcium and phosphate, but also contains varying amounts of water and hydrogen and hydroxide ions, depending on the synthesis conditions.[1] Such mixtures are also known as calcium phosphate cement.[2]
This article may be too technical for most readers to understand. (July 2017) |
ACP is generally categorized into either "amorphous tricalcium phosphate" (ATCP) or calcium-deficient hydroxyapatite (CDHA). CDHA is sometimes termed "apatitic calcium triphosphate."[1][3][4] The composition of amorphous calcium phosphate is CaxHy(PO4)z·nH2O, where n is between 3 and 4.5. CDHA has a general formula of Ca9(HPO4)(PO4)5(OH).[4] Precipitation from a moderately supersaturated and basic solution of a magnesium salt produces amorphous magnesium calcium phosphate (AMCP), in which magnesium incorporated into the ACP structure.[5]
A commercial preparation of ACP is casein phosphopeptide-amorphous calcium phosphate (CPP-ACP), derived from cow milk. It is sold under various brand names including Recaldent and Tooth Mousse, intended to be applied directly to teeth. Its clinical usefulness is unproven.[6]