NEUROG1_(gene)

NEUROG1
Identifiers
Aliases	NEUROG1, AKA, Math4C, NEUROD3, bHLHa6, ngn1, neurogenin 1
External IDs	OMIM: 601726 MGI: 107754 HomoloGene: 4490 GeneCards: NEUROG1
Gene location (Human)
Chr.	Chromosome 5 (human)
End	135,535,964 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	56,399,976 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence;
	Top expressed in
	urethra; ; female urethra; ; male urethra; ; rhombic lip; ; trigeminal ganglion; ; Jacobson's organ; ; pretectal area; ; main bronchus; ; somite; ; tongue;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; protein dimerization activity; DNA-binding transcription factor activity; chromatin binding; protein binding; protein homodimerization activity; E-box binding; sequence-specific double-stranded DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	perikaryon; neuronal cell body; nucleus;
Biological process	regulation of neuron differentiation; neurogenesis; cell differentiation; cell fate commitment; regulation of transcription, DNA-templated; regulation of transcription by RNA polymerase II; positive regulation of DNA-binding transcription factor activity; positive regulation of exit from mitosis; transcription, DNA-templated; nervous system development; multicellular organism development; positive regulation of neuron differentiation; neuron differentiation; positive regulation of transcription by RNA polymerase II; thorax and anterior abdomen determination; trigeminal nerve development; vestibulocochlear nerve formation; peristalsis; auditory behavior; genitalia morphogenesis; inner ear morphogenesis; regulation of muscle organ development; genitalia development; inner ear development; neuromuscular process controlling balance; mastication; cochlea development; cochlea morphogenesis; craniofacial suture morphogenesis; learned vocalization behavior; negative regulation of relaxation of muscle; negative regulation of saliva secretion; hard palate morphogenesis;
	Sources:Amigo / QuickGO
Orthologs
	4762
	18014
	ENSG00000181965
	ENSMUSG00000048904
	Q92886
	P70660
	NM_006161
	NM_010896
	NP_006152
	NP_035026
	Wikidata
View/Edit Human	View/Edit Mouse

Neurogenin-1

Protein-coding gene

Neurogenin-1 is a protein that in humans is encoded by the NEUROG1 gene.^[5]^[6]

Quick Facts NEUROG1, Identifiers ...

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This article uses material from the Wikipedia article NEUROG1_(gene), and is written by contributors. Text is available under a CC BY-SA 4.0 International License; additional terms may apply. Images, videos and audio are available under their respective licenses.

[refGRCh38Ensembl-1] [1]
GRCh38: Ensembl release 89: ENSG00000181965 – Ensembl, May 2017

[refGRCm38Ensembl-2] [2]
GRCm38: Ensembl release 89: ENSMUSG00000048904 – Ensembl, May 2017

[3] [3]
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] [4]
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9119405-5] [5]
Tamimi RM, Steingrimsson E, Montgomery-Dyer K, Copeland NG, Jenkins NA, Tapscott SJ (Mar 1997). "NEUROD2 and NEUROD3 genes map to human chromosomes 17q12 and 5q23-q31 and mouse chromosomes 11 and 13, respectively". Genomics. 40 (2): 355–7. doi:10.1006/geno.1996.4578. PMID 9119405.

[entrez-6] [6]
"Entrez Gene: NEUROG1 neurogenin 1".

[pmid11239394-7] [7]
Sun Y, Nadal-Vicens M, Misono S, Lin MZ, Zubiaga A, Hua X, Fan G, Greenberg ME (Feb 2001). "Neurogenin promotes neurogenesis and inhibits glial differentiation by independent mechanisms". Cell. 104 (3): 365–76. doi:10.1016/S0092-8674(01)00224-0. PMID 11239394. S2CID 1534352.

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[4]

[7]

NEUROG1_(gene)

Neurogenin-1

Interactions

References

Further reading

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