Michael Powell (1905–1990) was a British film director.

Mike Powell (long jumper) (born 1963) is a U.S. athlete, the world record holder in the long jump.

Michael Powell and/or Mike Powell may also refer to:

• Mike Powell (rugby union) (born 1978), rugby union player for the Ospreys
• Michael Powell (lacrosse) (born 1982), U.S. professional lacrosse player
• Mike Powell (cricketer, born 1975), English cricketer
• Mike Powell (cricketer, born 1977), Welsh cricketer

• Michael Powell (Louisiana politician), American politician from Louisiana
• Michael Powell (Massachusetts politician), a colonial Massachusetts politician
• Mike Powell (radio executive), early UK advocate of radio automation
• Michael Powell (lobbyist) (born 1963), attorney, former chairman of the U.S. Federal Communications Commission, son of Colin Powell
• Michael Powell (bookseller), owner of a well-known U.S. bookstore
• Michael J. Powell, American R&B musician
• Michael J. D. Powell (1936–2015), British applied mathematician
• Michael Warren Powell, theatre artistic director, director, actor and designer

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