In anatomy, a lobe is a clear anatomical division or extension^[1] of an organ (as seen for example in the brain, lung, liver, or kidney) that can be determined without the use of a microscope at the gross anatomy level. This is in contrast to the much smaller lobule, which is a clear division only visible under the microscope.^[2]

Interlobar ducts connect lobes and interlobular ducts connect lobules.

• The four main lobes of the brain
  • the frontal lobe
  • the parietal lobe
  • the occipital lobe
  • the temporal lobe
• The three lobes of the human cerebellum
  • the flocculonodular lobe
  • the anterior lobe
  • the posterior lobe
• The two lobes of the thymus
• The two and three lobes of the lungs
  • Left lung: superior and inferior
  • Right lung: superior, middle, and inferior
• The four lobes of the liver
  • Left lobe of liver
  • Right lobe of liver
  • Quadrate lobe of liver
  • Caudate lobe of liver
• The renal lobes of the kidney
• Earlobes