This list of tallest buildings in Guiyang ranks skyscrapers in Guiyang, Guizhou, China by height. The tallest building in Guiyang is currently the Guiyang International Financial Center, which rises 401 m (1,315 feet).

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This lists ranks Guiyang skyscrapers that stand at least 95 m (311 feet) tall, based on standard height measurement. This includes spires and architectural details but does not include antenna masts. Existing structures are included for ranking purposes based on present height. All the structures in this list has been topped, but some may not be ready to use.