The following is a List of senators of Seine-et-Oise, people who have represented the former department of Seine-et-Oise in the Senate of France. The department was dissolved in 1968, with most of its territory becoming the new departments of Essonne, Yvelines and Val-d'Oise.

• Charles Gilbert-Boucher (1876–1886)
• Léon Say (1876–1889)
• Ernest Feray (1876–1891)
• Hippolyte Maze (1886–1891)
• Louis Journault (1886–1892)
• Paul Decauville (1890–1900)
• Paul Maret (1891–1906)
• Ernest Hamel (1892–1898)
• Alphonse Chodron de Courcel (1892–1919)
• Frédéric Bonnefille (1898–1909)
• Louis Legrand (1900–1909)
• Arsène Collet (1907)
• Henri Poirson (1907–1923)
• Camille Ferdinand Dreyfus (1909–1915)
• Émile Aimond (1909–1917)
• Hugues Le Roux (1920–1925)
• Maurice Guesnier (1920–1927)
• Georges Berthoulat (1920–1930)
• Honoré Cornudet des Chaumettes (1924–1936)
• Louis Amiard (1926–1935)
• Georges Leredu (1927–1936)
• Louis Muret (1930–1936)
• Paul Brasseau (1936–1940)
• Maurice Dormann (1936–1940)
• Gaston Henry-Haye (1936–1940)
• Charles Reibel (1936–1940)

• Alain Poher (1946–1948 et de 1952–1959)
• Serge Lefranc (1946–1948)
• Pierre Pujol (1946–1952)
• Marie Roche (1946–1952)
• Jacqueline Thome-Patenôtre (1946–1959)
• Antoine Demusois (1948–1951)
• André Diethelm (1948–1951)
• Gabriel Bolifraud (1948–1952)
• Pierre Loison (1948–1952)
• Louis Namy (1951–1959)
• Xavier Pidoux de La Maduère (1951–1959)
• Antoine Boutonnat (1952–1958)
• Pierre Commin (1952–1958)
• Roger Lachèvre (1952–1959)
• René Boudet (1958–1959)
• Auguste Chrétienne (1958–1959)

Senators served one term under the French Fifth Republic, from 1959 to 1968, after which the department was dissolved.