Knucklehead may refer to:

• Harley-Davidson Knucklehead engine, introduced in 1936 as Model E, Harley-Davidson's first OHV engine
• Knucklehead (2015 film), a film directed by Ben Bowman
• Knucklehead (2010 film), a film produced by WWE Studios
• Knucklehead (band), a Canadian punk rock group formed in Calgary, Canada in 1994
• Knucklehead, B-side on the 1967 single "Soul Finger" by The Bar-Kays
• Knucklehead, song by Grover Washington Jr., from the 1975 album Feels So Good
• Knuckleheads, 2012 Canadian animated series
• Knuckleheads Saloon, Kansas City, Missouri (where Karla Bonoff, Leon Redbone, and others have appeared)
• Knuckle Heads, 1992 arcade game by Namco
• Knuckleheads, 2008 platform game by Nitrome Limited
• Knuckleheads Indoor Amusement Park, at Wisconsin Dells Parkway, Lake Delton, Wisconsin
• Knucklehedz, member of hip hop collective Hit Squad

Look up knucklehead in Wiktionary, the free dictionary.

• Knucklehead, the Mascot of the band Five Finger Death Punch
• Knucklehead Smiff, ventriloquist dummy of Paul Winchell
• Knucklehead, from The Pee-wee Herman Show stage show and the Pee-wee's Playhouse television series
• Knucklehead, from the anime Battle Angel Alita
• The Knuckleheads, nickname of The Three Stooges

This disambiguation page lists articles associated with the title Knucklehead.
If an internal link led you here, you may wish to change the link to point directly to the intended article.